David Moyes’ men now appear to be third or fourth favourites to clinch a Champions League qualification place through their Premier League position… but it is still up for grabs with five games remaining.
Meanwhile, Chelsea look a safe bet to secure third place but will be keen to quash any Tottenham or Arsenal hopes of catching them before the end of the campaign.
This could be a major scalp for West Ham if they can win at Stamford Bridge – a result which would condemn the European champions to a fourth straight home defeat.
Here’s everything you need to know ahead of today’s match.
When is Chelsea vs West Ham?
The match will kick off at 2pm BST on Sunday 24 April.
How can I watch it online and on TV?
It will be shown live on Sky Sports Main Event and Sky Sports Premier League with coverage starting at 1pm.
Tuchel was already missing Antonio Rudiger before his replacement Andreas Christensen suffered an injury during the Arsenal loss and is still set to be missing for this one. Malang Sarr suffered a difficult evening in the London derby, so Trevoh Chalobah could come back into the fold alongside Thiago Silva. Mateo Kovacic, Ben Chilwell and Callum Hudson-Odoi all remain sidelined, with Ross Barkley also a doubt.
Moyes has a serious centre-back crisis less than a week out from their crucial Europa League semi-final first leg. Issa Diop has joined Angelo Ogbonna and Kurt Zouma on the injury list as West Ham prepare to drop Declan Rice into the defence to play alongside Craig Dawson.
Chelsea: Mendy; James, Silva, Chalobah, Alonso; Jorginho, Kante, Mount; Werner, Havertz, Pulisic.
West Ham: Fabianski; Coufal, Dawson, Rice, Cresswell; Soucek, Lanzini, Fornals; Bowen, Antonio, Benrahma.
Chelsea – 6/11
Draw – 7/2
West Ham – 28/5
Chelsea are coming off the back of a torrid performance against Arsenal in midweek and will be hoping they can bounce back. But this could well be the perfect match for them given West Ham have their huge Europa League semi-final first leg in four days time. 2-0 Chelsea.